Immunology

Specific IgE Assay for Respiratory Allergens in Patients with Atopy in Ahvaz, Iran

مروری بر معتبرترین مجله‌های ایمنی‌شناسی در سال 2018: یک مطالعه توصیفی

Background and Objectives: Immunology is the science of prevention of entry and encounter with internal and external antigenes, with the aim of preserving the body's natural homeostasis. Due to the importance of immunology in prevention and treatment of diseases and concerning the multiplicity of published journals in this field, this study was performed to introduce the most prestigious specia...

Inherited Classical and Alternative Pathway Complement Deficiencies in Children: A Single Center Experience

Reference Values of Lymphocyte Sub-Populations in Healthy Human Immunodeficiency Virus-Negative Iranian Adults

Background: Lymphocyte subsets enumeration is considered prominent in the management of primary and acquired immunodeficiency disorders. Because of local variations due to race, age, gender, and environmental conditions on lymphocyte subsets, and to improve the accuracy of interpretation of laboratory findings, reference intervals must be determined in every population. Objective: To establish ...

Indoleamine 2,3-Dioxygenase and Immunological Tolerance during Pregnancy

Indoleamine 2,3-dioxygenase (IDO), an enzyme involved in the catabolism of tryptophan, is expressed by a variety of cells and tissues such as macrophages, dendritic cells, cells of the endocrine system and by the placenta. IFN- γ is the main inducer of this enzyme. IDO acts as an important defense mechanism of innate immunity against pathogens. It also has tumor suppressive activity and prolong...

Personalized Immunology in Cancer: Paving the Way Towards a Better Quality of Life

Conventionally, in specific diseases, patients receive similar therapies; relying on a "one size fits all" approach. The discovery of P5 (Predictive, Preventive, Personalized, Participatory, and psycho-cognitive) improves personalized diagnosis, treatment, and prognosis. Considering the high prevalence, mortality rate, and complexity of cancers, there is a critical necessity to choose specific ...